Two sample MR report
EIF5A_T Proliferating against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.1655041 | 0.1351228 | 0.3453167 |
| Weighted median | 4 | 0.0317273 | 0.0142974 | 0.0264799 |
| Inverse variance weighted | 4 | 0.0247481 | 0.0124440 | 0.0467277 |
| Simple mode | 4 | 0.0341950 | 0.0203570 | 0.1915941 |
| Weighted mode | 4 | 0.0345455 | 0.0199649 | 0.1820104 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.4459011 | 2 | 0.8001544 |
| Inverse variance weighted | 1.5402997 | 3 | 0.6730009 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0691693 | 0.0661189 | 0.4052977 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 7.52e-05 | 0 | TRUE | 0.4107649 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
